Effects of SeO2 on regulatory regions p250 of c-fos gene

Autor:	Long-yun Li, Xiao-zhe Cao, Hai-jian Yu, Mei-lan Zhao
Rok vydání:	2003
Předmět:	Cancer Research Tumor cells Transfection Biology Biological effect biology.organism_classification Molecular biology c-Fos HeLa Plasmid Oncology Regulatory sequence biology.protein Gene
Zdroj:	Chinese Journal of Cancer Research. 15:55-57
ISSN:	1993-0631 1000-9604
DOI:	10.1007/s11670-003-0012-4
Popis:	Objective: This study was designed to determine whether regulatory regions p250 of c-fos gene were responsive to SeO2 and to seek the possible mechanisms of regulation. Methods: HeLa cells were transfected with plasmids p250-tk CAT containing upstream regulating regions of c-fos gene. Cells were treated by SeO2 for 20 min. CAT expression in transfected cells was observed by thin layered chromatography. Results: In transfected HeLa cells CAT expression showed obvious increase after exposure to SeO2, especially in 10 µmol/L and 30 µmol/L group (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::df019120171d8d08184d31ac5ee8c0dd https://doi.org/10.1007/s11670-003-0012-4 Zobrazit plný text záznamu Full text from SpringerLink