| Autor: |
Paolo Perlini, Maria Elena Marongiu, Palmarisa Franchetti, Mario Grifantini, Paolo La Colla, Ghassan Abu Sheikha, M. Putzolu, Graziella Perra, Farhat Farhat, C. Milia |
| Rok vydání: |
1997 |
| Předmět: |
|
| Zdroj: |
Nucleosides and Nucleotides. 16:1921-1932 |
| ISSN: |
0732-8311 |
| DOI: |
10.1080/07328319708002544 |
| Popis: |
The synthesis of 9-[2-(phosphonomethoxy)allyl]guanine (1) and 9-[2-(phosphonomethoxy)allyl]-8-aza-guanine (2), two new unsaturated acyclic phosphonate nucleosides analogues of the anti-HIV agents PMPG and 8-aza-PMPG, is described. Compounds 1 and 2 were evaluated for activity against human immunodeficiency virus (HIV-1 and HIV-2) and herpes simplex virus (HSV-1 and HSV-2). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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