A Chemobiological Synthesis of Eplerenone

Autor: Scott W. Ashford, Michael P. Goble, R. E. Hrab, Michael J. White, Doris Beck, Andrew M. Anderson, Peter G. M. Wuts, Ivan G. Gilbert
Rok vydání: 2008
Předmět:
Zdroj: Synlett. 2008:418-422
ISSN: 1437-2096
0936-5214
DOI: 10.1055/s-2008-1032064
Popis: This paper will describe an approach to the synthesis of eplerenone, which is being marketed for the treatment of hypertension. The synthesis begins with DHEA available from wild yams and uses a combination of microbiological and chemical transformations to build eplerenone.
Databáze: OpenAIRE