A Chemobiological Synthesis of Eplerenone
Autor: | Scott W. Ashford, Michael P. Goble, R. E. Hrab, Michael J. White, Doris Beck, Andrew M. Anderson, Peter G. M. Wuts, Ivan G. Gilbert |
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Rok vydání: | 2008 |
Předmět: | |
Zdroj: | Synlett. 2008:418-422 |
ISSN: | 1437-2096 0936-5214 |
DOI: | 10.1055/s-2008-1032064 |
Popis: | This paper will describe an approach to the synthesis of eplerenone, which is being marketed for the treatment of hypertension. The synthesis begins with DHEA available from wild yams and uses a combination of microbiological and chemical transformations to build eplerenone. |
Databáze: | OpenAIRE |
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