Proliferative Retinopathies in Children
Autor: | Steven Awner, Philip J. Ferrone |
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Rok vydání: | 2010 |
Předmět: |
Retina
medicine.medical_specialty genetic structures business.industry Ischemia Retinal detachment Retinal Diabetic retinopathy medicine.disease eye diseases Neovascularization chemistry.chemical_compound medicine.anatomical_structure chemistry Ophthalmology Vitreous hemorrhage medicine sense organs medicine.symptom business Retinopathy |
Zdroj: | Pediatric Retina ISBN: 9783642120404 |
Popis: | The first two entities, diabetes and SC, develop retinopathy based upon a systemic metabolic disruption of retinal physiology. The other proliferative retinopathies, except for chronic retinal detachment, are due to either genetic or developmental abnormalities. They all exert their deleterious effects by inducing ischemia and thereby disrupting the metabolic needs of the retina. This invariably leads to neovascularization (NV) of the retina with resultant glial organization with or without hemorrhage into the vitreous. Subsequent contraction of the vitreous gel causes retinal detachment and often blindness. |
Databáze: | OpenAIRE |
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