Lymph node retrieval from colorectal resection specimens for adenocarcinoma: is it worth the extra effort to find at least 12 nodes?

Autor:	Richard B. Mertens, Mary Levy, Lifang Fan, Deepti Dhall, C. E. Aguilar, Hanlin L. Wang, David P. Frishberg
Rok vydání:	2011
Předmět:	medicine.medical_specialty business.industry Colorectal cancer Gastroenterology Cancer medicine.disease Surgery Metastasis Dissection medicine.anatomical_structure Carcinoma medicine Adenocarcinoma Lymph business Lymph node
Zdroj:	Colorectal Disease. 13:1377-1383
ISSN:	1462-8910
DOI:	10.1111/j.1463-1318.2010.02472.x
Popis:	Aim Retrieval of a minimum of 12 lymph nodes has been recommended for adequately staging a node-negative colorectal cancer (CRC). This study was designed to determine whether the extra effort expended to recover more nodes for histological examination improves the accuracy of staging. Method Pathology reports, histology worklists, and haematoxylin and eosin (H&E) slides of 334 CRC resections were reviewed. The total number of nodes and the number of positive nodes harvested from the first and additional searches were recorded for each patient. Results The number of nodes retrieved from the 334 resections at the first search ranged from 0 to 57 (mean: 14.2), with 195 patients (58.4%) having ≥ 12 nodes. Nodal metastasis was found in 122 (33.6%) patients. Additional searches were performed on 115 patients, including 91 with
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dee5b0de7e74d563069adb1b9b6f00a3 https://doi.org/10.1111/j.1463-1318.2010.02472.x Zobrazit plný text záznamu Plný text