| Autor: |
C. E. Schweitzer, Sandra G. Vincent, C. A. Escudero, John T. Fisher, J. L. Johnson |
| Rok vydání: |
2008 |
| Předmět: |
|
| Zdroj: |
Integration in Respiratory Control ISBN: 9780387736921 |
| DOI: |
10.1007/978-0-387-73693-8_31 |
| Popis: |
The activity of airway slowly adapting mechanoreceptors (SARs) reflects the presence of both a static and dynamic component. The dynamic response is typically assessed by the adaptation index; however, this is an indirect reflection of the more appropriate physiological stimulus, the rate of change of inflation pressure (dp/dt). We describe a method in which measurement of receptor discharge exceeding the SAR static response is used to measure dynamic discharge and dynamic sensitivity of lung mechanoreceptors. Repeat inflations with varying dp/dt illustrate the method for a SAR in which the dynamic sensitivity is inversely related to dp/dt and the initial "onset" discharge is highly dp/dt sensitive. The method may provide new insight into the classification and behaviour of lung mechanoreceptors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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