| Popis: |
Thyroid disease is a common endocrinopathy seen in pregnancy with hypothyroidism being the most common followed by thyrotoxicosis. The most common etiology of thyrotoxicosis in pregnant women is Graves’ disease, followed by transient thyrotoxicosis of pregnancy. Laboratory testing, history, and physical exam can delineate the differential diagnosis in most cases. Imaging is often not required. Untreated thyrotoxicosis can lead to adverse outcomes for both the mother and fetus, and patients can present on a wide spectrum of severity of thyrotoxicosis spanning from mild subclinical hyperthyroidism to thyroid storm with multi-organ failure. Treatment of hyperthyroidism, if warranted, is typically pharmacological therapy with antithyroidals called thionamides. Frequent monitoring is crucial for successful therapy to ensure the most optimal outcomes. The following chapter is a review of these concepts covering diagnosis, maternal and fetal risks of thyrotoxicosis, treatment, and follow-up. |
