Partition Control Scheme for Better Controllability of Drug Release Rate in BioMEMS Delivery Device

Autor: Meenubharathi Natarajan, Subbu S. Venkatraman, Hejun Du, Sam Zhang, Lei Shang
Rok vydání: 2010
Předmět:
Zdroj: Nanoscience and Nanotechnology Letters. 2:11-15
ISSN: 1941-4919
1941-4900
Popis: School of Materials Science and Engineering,Nanyang Technological University, Singapore 639798Hydrogel has been combined with standard Bio-Microelectromechanical Systems (BioMEMS) torealize self-controllable pulsatile drug delivery. One of the key problems with hydrogel basedBioMEMS drug delivery system is its poor controllability. A drug immobilization partition controlscheme is applied to a positively triggered hybrid system for controllability. With suitable amountof drug immobilization, the switching effectiveness is increased drastically from 43.6% to 140%.
Databáze: OpenAIRE