Abstract 284: Association of Worsening Renal Function With Mortality and Heart Failure Readmissions in Patients Hospitalized With Acute Heart Failure
| Autor: | Jacqueline B Palmer, Howard Friedman, Katherine Waltman Johnson, Prakash Navaratnam, Stephen S Gottlieb |
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| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Circulation: Cardiovascular Quality and Outcomes. 8 |
| ISSN: | 1941-7705 1941-7713 |
| Popis: | Background: The impact of worsening renal function (WRF) on heart failure (HF)-related readmissions (HFR) and HF-related mortality among hospitalized acute HF patients was examined. Methods: A patient’s first acute HF hospitalization event (index) was identified in Cerner Health Facts® database (Jan 2008–March 2011). Patients were categorized as WRF (serum creatinine ≥0.3 mg/dL and ≥25% increase from baseline) persisting at discharge (WRFp), not persisting at discharge (WRFt), or non WRF. Outcomes were compared for the index hospitalization and cumulatively at 30, 180, and 365 days post discharge. Generalized linear model (HFR count) and logistic regression models (mortality) were constructed. Results: The acute HF patients (77% [42,507 of 55,436] non WRF, 10% [5,563 of 55,436] WRFp, and 13% [7,366 of 55,436] WRFt) were 53% [29,442 of 55,436] female with a mean age of 72.4 (±14.3) years. WRFp had higher index mortality rates (23.6% [1,312 of 5,563] vs 5.7% [418 of 7,366] vs 3.9% [1,673 of 42,507], P Conclusion: Acute HF patients with WRF were more likely to die or be readmitted than non WRF patients. WRFp patients experienced higher HF-related mortality rates than WRFt patients but there were no differences in HFR between WRFt and WRFp. |
| Databáze: | OpenAIRE |
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