Outcome of surgical and endoscopic lung volume reduction with valves in patients with severe lung emphysema: current data of 246 patients with 3 months follow-up from a Lung Emphysema Registry in Germany
| Autor: | Stefan Eggeling, Gunda Leschber, Ralf-Harto Hübner, Jens-Carsten Rückert, Andreas Gebhardt, Birgit Becke, Bernd Schmidt, Pavlina Lenga, Christian Grah, Sylke Kurz, Paul M. Schneider, Joachim Pfannschmidt |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Lung volume reduction
medicine.medical_specialty business.industry Mortality rate respiratory system respiratory tract diseases Surgery 03 medical and health sciences High morbidity 0302 clinical medicine 030228 respiratory system Quality of life DLCO medicine In patient Lung emphysema Observational study 030212 general & internal medicine business |
| Zdroj: | Thoracic surgery. |
| DOI: | 10.1183/13993003.congress-2020.4095 |
| Popis: | Introduction: Lung emphysema is associated with high morbidity and mortality rates. Both surgical lung volume reduction (LVRS) and endoscopic lung volume reduction with valves (ELVR-V) seem to produce good clinical outcomes.However, a systematical comparison of different treatment approaches is still missing. The main goal of the Lung Emphysema Registry (LE-R) is to analyze types of treatment applied to patients with severe lung emphysema and to describe outcomes in relation to treatment techniques over time. Methods: The LE-R is a multicenter non-randomized prospective clinical study, which is collecting data exclusively on patients with lung emphysema treated at specialized centers. The patients were followed up after 3 months, and the lung function (FEV1, RV, VC, DLCO), the clinical status, quality of life (CAT and mMRC) and exercise capacity (6-MWT) were documented. Results: Since 2017 246 patients were included. Table 1 displays improvements in lung function and quality of life in both groups at 3mo FU. Conclusions: These novel findings suggest that both techniques are beneficial to patients with severe emphysema up to 3 months after intervention in a real-world observational study. Future analyses might help to define which treatment types should be applied to the specific patients subgroups. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|