Phosphofructokinase from a mouse preputial gland tumour ESR-58

Autor:	Murray R. Grigor, Arie Geursen
Rok vydání:	1980
Předmět:	chemistry.chemical_classification Enzyme Biochemistry chemistry Effector Allosteric regulation Preputial gland Biology Mouse Preputial Gland Phosphofructokinase
Zdroj:	International Journal of Biochemistry. 12:433-437
ISSN:	0020-711X
DOI:	10.1016/0020-711x(80)90124-x
Popis:	1. 1. Phosphofructokinase from botli the mouse preputial gland tumour and the gland itself have electrophoretic properties similar to the enzyme from mouse brain. 2. 2. The tumour enzyme showed allosteric kinetics with respect to both substrates and was similar to the brain in the response to a number of known effectors of phosphofructokinase. 3. 3. The tumour enzyme was however less sensitive to AMP activation and more sensitive to 2,3-diphosphoglycerate inhibition than the brain enzyme. 4. 4. Phosphofructokinase from the preputial gland was similar to the enzyme from brain in its response to AMP, but was intermediate between those of the tumour and brain in its sensitivity to 2,3-diphosphoglycerate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::de6168e0bc806e35cbdef81bb9f8ec1a https://doi.org/10.1016/0020-711x(80)90124-x Zobrazit plný text záznamu