Abstract WP239: Stroke Mimics Treated with Thrombolysis: A Single Center Experience

Autor: Sonal Mehta, Nirav Vora, Hesham Allam, Aws Alawi, Jennifer Koehne, Fahad Alobaidi, Ritesh Kaushal, Salvador Cruz-Flores, Amer Alshekhlee
Rok vydání: 2013
Předmět:
Zdroj: Stroke. 44
ISSN: 1524-4628
0039-2499
Popis: Background: Recent reports suggested better outcomes associated with the drip-and-ship paradigm for acute ischemic stroke (AIS) treated with thrombolysis. Alternative hypothesis is a higher rate of stroke mimics (SM) among AIS treated in a non-specialized stroke centers and then transferred to comprehensive centers. Methods: Consecutive patients treated with thrombolysis according to the admission criteria were reviewed in a single comprehensive stroke center over one academic year. Information on the basic demographic, hospital complications, psychiatric diagnoses, and discharge information were collected. We also identified those who were treated in outside facility and then transferred to the tertiary center (i.e. drip-and-ship paradigm). Comparative and adjusted analysis to identify predictors for stroke mimics was performed. Results: 120 patients were treated with thrombolysis for AIS included in this analysis; 20 (16.7%) were discharged with the final diagnosis of SM; 14 of those had conversion syndrome and 6 patients had other syndromes (seizures, migraine, and hypoglycemia). Patients with SM were younger (55.6 ± 15.0 versus 69.4 ± 14.9, P = 0.0003), had a slight female preponderance (55% versus 46%; P = 0.46); and more likely to harbor a psychiatric diagnosis (45% versus 9%; P = Conclusion: Drip-and-ship paradigm and the presence of any psychiatric history predict the diagnosis of SM. None of the SM had any thrombolysis related complication and all were discharged to home. These findings may explain the superior outcomes associated with the drip-and-ship paradigm in the treatment of AIS
Databáze: OpenAIRE