PHYSIOLOGICAL AND REPARATIVE OSTEOGENESIS IN THE NORM AND UNDER CONDITIONS OF SELENIUM DEFICIENCY

Autor:	I G Biryuk, S V Tulyulyuk, Kovalchuk P. Ye.
Rok vydání:	2019
Předmět:	Pathology medicine.medical_specialty business.industry Cartilage Regeneration (biology) chemistry.chemical_element medicine.disease Bone tissue medicine.anatomical_structure Traumatic injury chemistry Selenium deficiency Male rats medicine Femoral bone business Selenium
Zdroj:	World Science. 2:17-20
ISSN:	2414-6404 2413-1032
Popis:	The study presents the results of investigation of selenium deficiency condition on the bone tissue and healing post-traumatic bone defects under conditions of selenium deficiency.The experimental part of the study was performed on 63 randomized brand albino male rats of 3-month age. Peculiarities of the reparative osteogenesis were studied on the model of a traumatic injury simulated one-type in the proximal meta-diaphysis of the femoral bone irrespective of the experimental conditions in the frontal plane in the form of perforated defect. The defect was made by means of a drill 1mm in diameter.The results of the study are indicative of a negative effect of selenium deficiency produced on physiological and reparative osteogenesis manifested by inhibition of the process and associated with disorders in the formation of osseous regeneration, deterioration of the structural-functional state of the osseous tissue, development of degenerative-necrotic changes in the osseous tissue and epiphyseal cartilage.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::de2f599ca5f94c73345beee8a1c6b919 https://doi.org/10.31435/rsglobal_ws/31082019/6632 Zobrazit plný text záznamu