Diffuse Neuronal Perikaryon Amyloid Precursor Protein Immunoreactivity in a Focal Head Impact Model

Autor: Stephen B. Lewis, Peter C. Blumbergs, Nigel R. Jones, Peter L. Reilly, James Manavis, C Van den Heuvel, M. Wong, J. W. Finnie
Rok vydání: 1998
Předmět:
Zdroj: Intracranial Pressure and Neuromonitoring in Brain Injury ISBN: 9783709173312
Popis: Amyloid precursor protein (APP) has been shown to accumulate in traumatically injured axons as early as 1 hour after injury. This accumulation may be due to interruption of fast axoplasmic transport and/or upregulation of APP synthesis. The aim of this study was to examine the neuronal cell body response to head impact using APP immunostaining in a focal non-missile head impact model.
Databáze: OpenAIRE