Efeitos de um salgante isento de sódio sobre marcadores sanguíneos bioquímicos hepáticos, renais e cardíacos de ratos normo e hipertensos

Autor:	Mário Ivo Serinolli, Afonso Caricati-Neto, Francisco Sandro Menezes-Rodrigues, Luciana de Paula, Leandro Bueno Bergantin, Alex Sandro Felisberto Oliveira, Marcos José da Silva, Alessandra de Oliveira Fantoni, Ricardo Thiago Paniza Ambrosio, Renato Ribeiro Nogueira Ferraz, Paolo Ruggero Errante
Rok vydání:	2017
Předmět:	Creatinine medicine.medical_specialty Aqueous solution medicine.medical_treatment Sodium chemistry.chemical_element General Medicine Creatine chemistry.chemical_compound Endocrinology chemistry Internal medicine Lactate dehydrogenase medicine Alkaline phosphatase Uric acid Saline
Zdroj:	ConScientiae Saúde. 16:217-223
ISSN:	1983-9324 1677-1028
DOI:	10.5585/conssaude.v16n2.7118
Popis:	Introduction: Hypertension is one of the risk factors for cardiovascular diseases, being directly associated with high consumption of sodium. Objective: To assess the levels of hepatic, renal and cardiac injury markers in hypertensive rats compared to their normotensive controls, treated with a salt free saline solution, water or NaCl. Methods: Hypertensive rats (SHR) and their normotensive controls (NWR) were divided into 3 groups (n = 7): G1 (water); G2 (aqueous solution containing NaCl 70 mg / kg / day); G3 (sodium salt-free aqueous solution 70 mg / kg / day). After 30 days, the animals’ blood was processed. Results: There was no difference between serum levels of total creatine kinase, creatine kinase-MB, lactate dehydrogenase, uric acid, aspartate aminotransferase and alkaline phosphatase in both NWR and SHR1 treated NaCl or Salgante. There was a decrease in creatinine in NWR and SHR treated with NaCl and Salgante comparing to controls (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::de0a5283c80e4d9c6e772bef90128ff5 https://doi.org/10.5585/conssaude.v16n2.7118 Zobrazit plný text záznamu