Structures of New Pseudo-Peptide Antibiotics, Sperabillins
| Autor: | Hideo Ono, Shigetoshi Tsubotani, Yasunori Funabashi, Tsuneaki Hida, Setsuo Harada |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
chemistry.chemical_classification
biology Stereochemistry Chemistry medicine.drug_class Antibiotics Substituent Absolute configuration Pseudomonas fluorescens Peptide General Chemistry Nuclear magnetic resonance spectroscopy biology.organism_classification Amidine chemistry.chemical_compound medicine Moiety |
| Zdroj: | Bulletin of the Chemical Society of Japan. 66:863-869 |
| ISSN: | 1348-0634 0009-2673 |
| Popis: | Sperabillins, novel antibiotics, were isolated from the culture filtrate of Pseudomonas fluorescens YK-437. The structure of sperabillin A was elucidated to be 3-[[(3R,5R)-3-amino-6-[(2E,4Z)-2,4-hexadienoylamino]-5-hydroxyhexanoyl]amino]propanamidine dihydrochloride. Sperabillin B has a methyl substituent at the C-6 position of sperabillin A. Sperabillin C and D are (2E,4E)-isomers of the 2,4-hexadienoyl moiety of sperabillin A and B, respectively. |
| Databáze: | OpenAIRE |
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