Nodular regenerative hyperplasia ofthe liver: the importance of combined macroscopic and microscopic findings

Autor:	Keith B. Shilkin, Geoffrey M Forbes, William D Reed
Rok vydání:	1991
Předmět:	Alcoholic liver disease Pathology medicine.medical_specialty medicine.diagnostic_test business.industry General Medicine Hyperplasia medicine.disease Liver biopsy Ascites medicine Portal hypertension medicine.symptom Stage (cooking) Varices business Nodular regenerative hyperplasia
Zdroj:	Medical Journal of Australia. 154:415-417
ISSN:	1326-5377 0025-729X
DOI:	10.5694/j.1326-5377.1991.tb121136.x
Popis:	A 40-year-old man with rheumatoid arthritis, splenomegaly and mild thrombocytopenia presented with gross ascites and a history of excess alcohol consumption. Oesophageal varices were documented endoscopically. Alcoholic cirrhosis was suspected and laparoscopy revealed a macronodular liver surface. Liver biopsy disclosed subtle microscopic structural variations which together with the laparoscopic findings were consistent with the diagnosis of nodular regenerative hyperplasia. The importance in diagnosis of macroscopic appearance combined with histological findings is emphasised. Clinically significant portal hypertension may be present at a histologically early stage of this condition.
Databáze:	OpenAIRE
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