The effect of combining fast neutron and photon irradiation on the human osteosarcoma OS-732 cell line

Autor: Dong Yang, Mingxue Sun, Jingxiang Huang, Yingxuan Wang, Chengxiang Liu, Weike Chang, Lin Ma, Linchun Feng, Jinhua Tang
Rok vydání: 2005
Předmět:
Zdroj: Chinese Journal of Clinical Oncology. 2:654-657
ISSN: 1993-5145
1672-7118
DOI: 10.1007/bf02739726
Popis: To determine the lethal effect of combining fast neutron with photon radiation on the OS-732 cell line. We examined the effect of irradiation by fast neutrons, photons and a mixed beam (fast neutrons plus photons) on the lethality and colony forming ability of the OS-732 cell line at different times. Following a single irradiation close, the lethality was markedly strong at 24, 48 and 72 h in the group treated with fast neutrons alone and in the mixed beam group in which there was a high proportion of fast neutrons. The lethal effect of a fast neutron and mixed beam with a high proportion of fast neutrons on the OS-732 cell line is highly significant. These studies provide guidance for the clinical application of fast neutrons for osteosarcoma treatment.
Databáze: OpenAIRE