The Behavior of Dimethylamino-Substituted 2,5-Diaryloxazoles and 2,5-Diaryl-1,3,4-oxadiazoles under Vilsmeier—Haack Conditions

Autor:	I. G. Ermolenko, B. M. Krasovitskii, I. A. Fedyunyaeva, Alexander V. Mazepa, O. N. Lyubenko, O. S. Galkina, N. A. Popova, Leonid D. Patsenker
Rok vydání:	2004
Předmět:	chemistry.chemical_compound Chemistry Group (periodic table) Stereochemistry General Medicine Ring (chemistry) Medicinal chemistry Oxazole
Zdroj:	ChemInform. 35
ISSN:	1522-2667 0931-7597
Popis:	It has been shown that dimethylamino-substituted 2,5-diaryloxazoles and 2,5-diaryl-1,3,4-oxadiazoles undergo heterocyclization under Vilsmeier-Haack conditions with the participation of the dimethylamino group to form quinazolinium salts. The oxazole ring can also be formylated at the free 4 position. In alkaline medium the quinazolinium ring is readily hydrolyzed with desalkylation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ddc2d32d9b15fa33f80e89d2bdb81b3c https://doi.org/10.1002/chin.200408149 Zobrazit plný text záznamu Plný text