Synthesis of polysubstituted 2,4-dimethylquinolines as potential antimalarial drugs

Autor:	Peter Nickel, Günther Snatzke, Yoncho Vlahov, R. Vlahov, Stoyan Parushev
Rok vydání:	1991
Předmět:	chemistry.chemical_compound chemistry Bicyclic molecule Nitration Quinoline Nitro General Chemistry Electrophilic aromatic substitution Alkylation Ring (chemistry) Combinatorial chemistry
Zdroj:	Collection of Czechoslovak Chemical Communications. 56:1110-1115
ISSN:	1212-6950 0010-0765
DOI:	10.1135/cccc19911110
Popis:	A synthetic way for obtaining 6-amino-2,4-dimethylquinoline derivatives from 2,5-dichloraniline by successive ring closure, nitration, aromatic substitution at so activated quinoline ring, followed by reduction of the nitro group to amino group and alkylation of the last is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ddbd63924b4d1c91d3a7bfe2f72b2753 https://doi.org/10.1135/cccc19911110 Zobrazit plný text záznamu