Dynamic Process of Colonization by Haemophilus influenzae in Children

Autor:	Atsushi TAKAHASHI, Masakazu TAKASUGI, Yoshiaki UTSUNOMIYA, Moritoshi AKIYAMA, Hidehiko HIROSE, Hironori MASAKI, Akitaka IWAGAKI, Kiwao WATANABE, Kamruddin AHMED, Misao TAO, Takeshi YAMARYO, Naoto RIKITOMI, Tsuyoshi NAGATAKE, Keizo MATSUMOTO
Rok vydání:	1992
Předmět:	Serotype medicine.anatomical_structure Throat medicine Normal flora Colonization General Medicine Biology medicine.disease_cause Haemophilus influenzae Microbiology
Zdroj:	Journal of the Japanese Association for Infectious Diseases. 66:956-963
ISSN:	1884-569X 0387-5911
DOI:	10.11150/kansenshogakuzasshi1970.66.956
Popis:	Eighty-seven oropharyngeal isolates of Haemophilus influenzae were obtained by two time cultures six months apart from a total of 288 children who attend a kindergarten. We analyzed the strains by comparing their serotypes, biotypes, beta-lactamase activity and by performing electrophoresis of outer membrane proteins on polyacrylamide gels. Only nineteen strains were not identical, the rest of the 68 strains were classified into 23 types. During 6 months at least 15 types of strains lost from this group and 21 types of new strains were obtained. There were no children who had identical pairs of H. influenzae in their oropharynx during the 6 months. The classification of strains in oropharynx suggested that person-to-person transmission of nontypable H. influenzae can occur. We concluded that oropharyngeal colonization by nontypable H. influenzae is not a normal flora in children.
Databáze:	OpenAIRE
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