| Autor: |
Edouard Massaut, Marie Therese Genot, Valerie Doriath, Rokneddin Javadian, Jean Klastersky |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Hospice and Palliative Medicine International Journal. 1 |
| ISSN: |
2576-4497 |
| Popis: |
Osteonecrosis of the jaw (ONJ) is a relatively rare but serious complication of bisphosphonates (and denosumab) therapy for which conservative or surgical treatment is advocated. We report an exemplative case and review recently published studies of surgical management of ONJ. The total population surveyed in those 7 studies included 1459 patients. Operative treatment was applied in 53-100% of the patients and non-operative treatment in 0-47%. Response after surgery was seen in 59-87% (actually 938 patients out of 1204-77% - responded). Non-operative treatment was successful in 20-100% (40 out of 250 – 16% - patients responded). The highest range of response was seen in stage 2 diseases (22-67%). Our review supports the use of a relatively early surgical approach in the management of ONJ. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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