New Amphiphilic Glycopolymers Based on a Polycaprolactone-maleic anhydride Copolymer Backbone: Characterization by15N NMR and Application to Colloidal Stabilization of Nanoparticles
| Autor: | Otman Otman, Thierry Hamaide, Dominique Lafont, Paul Boullanger |
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| Rok vydání: | 2008 |
| Předmět: |
Materials science
Polymers and Plastics Glycopolymer Organic Chemistry Nanoparticle Chemical modification Maleic anhydride Condensed Matter Physics Macromonomer chemistry.chemical_compound chemistry Polycaprolactone Polymer chemistry Amphiphile Materials Chemistry Copolymer Physical and Theoretical Chemistry |
| Zdroj: | Macromolecular Chemistry and Physics. 209:2410-2422 |
| ISSN: | 1521-3935 1022-1352 |
| DOI: | 10.1002/macp.200800300 |
| Popis: | 8-Amino-3,6-dioxaoctyl α-D-mannopyranoside and 8-amino-3,6-dioxaoctyl β-D-galactopyranoside were prepared for coupling with a copolymer made from PCL macromonomers and MA. The new glycosyl compounds as well as PCL macromonomers were synthesized by appropriate techniques and fully characterized. The grafting of the latter with the functionalized copolymer was ascertained by 15 N NMR experiments. The glycopolymers thus obtained were used in conjunction with Pluronic® F-68 for the stabilization of PCL nanoparticles prepared by the emulsification-diffusion technique. The stabilization of these nanoparticles upon storage and after centrifugation was investigated as well. |
| Databáze: | OpenAIRE |
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