Derivatives of hydroxybenzoic acids and their salts: Synthesis and pharmacological activity

Autor: A. K. Brel, S. V. Lisina, Yu. N. Budaeva
Rok vydání: 2015
Předmět:
Zdroj: Russian Journal of General Chemistry. 85:387-391
ISSN: 1608-3350
1070-3632
Popis: Preparation of salicylic and acetylsalicylic acid esters via esterification and alkylation of the salts with alkyl halides has been examined. The effect of the alkylating agent nature and the reaction conditions (catalyst and solvent) on yield of the target products has been elucidated. The biological properties of the resulting compounds can be modified by varying the nature of the alkali metal cation (K+, Na+, or Li+) of the salt form of hydroxybenzamides.
Databáze: OpenAIRE