Four-year follow-up on the Albany experience with intrapleural BCG in lung cancer
| Autor: | T M Older, Joseph B. McIlduff, Eric D. Foster, L. Lininger, Martin F. McKneally, Ralph D. Alley, HarveyW. Kausel, C. Maver |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty business.industry medicine.medical_treatment Bcg immunotherapy Disease Immunotherapy medicine.disease complex mixtures Surgery law.invention Clinical trial Randomized controlled trial law medicine Carcinoma Cardiology and Cardiovascular Medicine business Tuberculin test Lung cancer |
| Zdroj: | The Journal of Thoracic and Cardiovascular Surgery. 81:485-492 |
| ISSN: | 0022-5223 |
| DOI: | 10.1016/s0022-5223(19)39476-0 |
| Popis: | One hundred sixty-nine patients were entered into randomized controlled studies of intrapleural bacille Calmette Guerin (BCG) immunotherapy after surgical resection of lung cancer. Long-term follow-up of our initial series of BCG-treated patients with Stage I disease continues to indicate that this treatment was superior to that given to control patients. The recurrence rate in the control population was high, 62% at 3 years. The recurrence rate was 33% at 3 years in the BCG-treated group. A negative preoperative tuberculin test and squamous cell histologic type were favorable prognostic factors for BCG-treated patients. The survival of patients with more advanced disease was not improved by BCG immunotherapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|