| Popis: |
The immunocomplex vaccine against infectious bursal disease from the VNIVIP strain has strong immunogenic properties, including active expression of the IL-6 cytokine synthesis genes in the tissues of the bursa of Fabricius and cecum. This phenomenon stimulates a local non-specific immune response, resulting in a reduction in the representation of pathogenic and opportunistic microorganisms in the intestines of chickens. As a result of the studies, it was found that the relative expression in the tissues of the caecum of the intestines of chickens of the Loman White cross reached a 2.7-fold excess over the control level, and the relative expression in the tissues of the Fabricius bag - 15.6-fold excess over the control level. The relative content of bacteria of the Escherichia coli group, as sanitary indicative microorganisms, decreased by 4 times under the influence of the vaccine (from 0.253% in the control group to 0.064% in the vaccinated group). The variety of staphylococci under the influence of the vaccine was also reduced, and only unidentifiable representatives of the genus Staphylococcus were found in the vaccinated group. |
