MUCOADHESIVE BUCCAL DRUG DELIVERY SYSTEM: REVIEW ARTICLE
| Autor: | Monali Sonawane, Dattatrey Shinkar, Ravindrasaudagar |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
business.industry
Pharmaceutical Science 02 engineering and technology Buccal administration Pharmacology 021001 nanoscience & nanotechnology 030226 pharmacology & pharmacy Review article 03 medical and health sciences 0302 clinical medicine Drug delivery Medicine 0210 nano-technology business Biomedical engineering |
| Zdroj: | International Journal of Current Pharmaceutical Research. 9:1 |
| ISSN: | 0975-7066 |
| DOI: | 10.22159/ijcpr.2017v9i4.20960 |
| Popis: | The advantage of buccal drug delivery system over the conventional and systemic formulation majority. It helps enhance the bioavailability through bypassing the first-pass metabolism effect. The mucosal surface better absorption and prolong resident time. Bioadhesion can be defined as the phenomenon of interfacial molecular attractive force in midst of the surface of the biological substrate and the natural or synthetic polymers, which allows the polymers to adher to the biological surface for an extended period of time. Among the various transmucosal sites available, mucosa of the buccal cavity was found to be the most convenient and easily approachable site for the delivery of the therapeutic agent for both local and systemic delivery. This review also covers available marketed product as buccal drug delivery system and future aspects of buccal drug delivery system. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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