Sampling the fetoplacental circulation

Autor: Ezra C. Davidson, Michael M. Kaback, John P. O'Grady, John A. Morris, Robert Frazer, John Anderson, Andrew G Hendrickx
Rok vydání: 1978
Předmět:
Zdroj: American Journal of Obstetrics and Gynecology. 132:833-841
ISSN: 0002-9378
DOI: 10.1016/0002-9378(78)90709-3
Popis: To demonstrate increased technical experience with fetoscopy and fetal blood sampling, two groups of macaques were compared to control animals. Group 2 had a perinatal mortality rate that was not significantly different from that of the control group. A 2.7 mm. Hopkins rod lens endoscope encased in an eccentric cannula, 3.8 mm. outside diameter, was used. When compared to the earlier test group (Group 1), the later test group (Group 2) showed greater adequacy of the fetal blood sample for laboratory analysis (P less than 0.01). Anthropometric and hematologic data collected at term births compared favorably in test and control groups, with the exception of the white blood cell count, which was significantly lower with fetoscopy (P less than 0.01). This is the first report of experimental fetoscopy with the use of a control group to provide precise data to aid in clarification of the ethical issues yet unresolved in this technology.
Databáze: OpenAIRE