The prognostic importance of severity and type of post-transplant proteinuria
| Autor: | Isin Kilicarslan, Ecder St, R. Erkoç, Aydin Turkmen, E. Ark, Alaattin Yildiz, Mehmet Sukru Sever, Suleyman Turk |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Transplantation
medicine.medical_specialty Kidney Proteinuria Graft failure urogenital system business.industry urologic and male genital diseases medicine.disease Gastroenterology female genital diseases and pregnancy complications Post transplant Surgery medicine.anatomical_structure Internal medicine Allograft survival Medicine medicine.symptom business Complication Kidney disease |
| Zdroj: | Clinical Transplantation. 13:241-244 |
| ISSN: | 0902-0063 |
| DOI: | 10.1034/j.1399-0012.1999.130304.x |
| Popis: | Proteinuria, developing after renal transplantation may influence allograft and patient outcomes. This study aimed to investigate the effect of proteinuria on patient and allograft survival. Among 514 patients, 56 (11%) patients with good allograft function and proteinuria were evaluated retrospectively. Patients with proteinuria were classified as group P (20 patients with permanent proteinuria, Male/Female: 16/ 4) and group T (36 patients with temporary proteinuria, M/F: 29/7) according to the type of proteinuria. Also, considering the amount of proteinuria, patients were classified as group M (32 patients with massive proteinuria, M/F: 29/3) and group NM (24 patients with non-massive proteinuria, M/F: 16/8). The mean time interval between transplantation and appearance of proteinuria was 23.7 months (range 0-121 months) and no difference was found between groups. Two- and 5-yr allograft survival rates were found to be 85 and 80% in group M, and 95 and 82% in group NM, respectively (p = 0.24). In terms of type of proteinuria, 2- and 5-yr allograft survival rates were found to be 70 and 58% in group P and 92 and 87% in group T, respectively. The difference between groups P and T was found to be statistically significant (p = 0.02). Most (85%) of the patients with permanent proteinuria also had massive proteinuria. In conclusion, we found a significant relation between type and severity of proteinuria. The type of post-transplant proteinuria had a stronger effect on allograft outcome than the severity of proteinuria. |
| Databáze: | OpenAIRE |
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