Cell-to-cell fusion as a link between viruses and cancer

Autor:	Yuri Lazebnik, Dominik M. Duelli
Rok vydání:	2007
Předmět:	Genetics Cell fusion viruses Applied Mathematics General Mathematics fungi Cell food and beverages Cancer Cell cycle Biology medicine.disease Virus medicine.anatomical_structure Chromosome instability Cancer cell medicine Oncovirus
Zdroj:	Nature Reviews Cancer. 7:968-976
ISSN:	1474-1768 1474-175X
DOI:	10.1038/nrc2272
Popis:	The ability to fuse cells is shared by many viruses, including common human pathogens and several endogenous viruses. Here we will discuss how cell fusion can link viruses to cancer, what types of cancers it can affect, how the existence of this link can be tested and how the hypotheses that we propose might affect the search for human oncogenic viruses. In particular, we will focus on the ability of cell fusion that is caused by viruses to induce chromosomal instability, a common affliction of cancer cells that has been thought to underlie the malignant properties of cancerous tumours.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dd50e09788066a240f8b3bca362caa50 https://doi.org/10.1038/nrc2272 Zobrazit plný text záznamu Plný text ve formátu PDF