Amoxicillin—Omeprazole Treatment for Eradication of Helicobacter pylori
| Autor: | E. Gyenes, G. H. Rühl, J. Labenz, G. Börsch |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
medicine.medical_specialty
biology medicine.drug_class business.industry Antibiotics Helicobacter pylori Amoxicillin biology.organism_classification Gastroenterology Amoxicillin/omeprazole Spiral bacterium Internal medicine medicine Etiology Gastritis medicine.symptom business Omeprazole medicine.drug |
| Zdroj: | Helicobacter pylori and Gastroduodenal Pathology ISBN: 9783642774881 |
| Popis: | The spiral bacterium Helicobacter pylori is regarded as the causal factor in chronic type B gastritis and is said to play a co-causal role in the etiology of peptic ulcer disease. This bacterium is gaining increasing importance in practical gastroenterology since it could be shown that an eradication of the bacterium is accompanied by an improvement or healing of gastritis [9]. Also, the frequency of ulcer recurrences can be reduced substantially and significantly [1, 6,10]. Up to now, eradication of H. pylori in a high percentage of cases (80%–94%) required elaborate triple therapy schedules consisting of a bismuth salt and a double antibiotic combination [2, 4]. A simple schedule of short-term therapy with low complications and adequate efficiency is still not available. Amoxicillin and omeprazole on their own bring about at best an elimination of the bacteria in individual cases [5]. In this connection, Unge et al. [12] were able to show in a small-scale study that the combination of omeprazole and amoxicillin led to an eradication in five out of eight patients, whereas omeprazole and amoxicillin alone were ineffective in the control groups. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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