Standardization of Measurements for Cholesterol, Triglycerides, and Major Lipoproteins
| Autor: | Elizabeth T. Leary, G. Russell Warnick, Mary M. Kimberly, Parvin P. Waymack, Gary L. Myers |
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| Rok vydání: | 2008 |
| Předmět: |
Ldl cholesterol
medicine.medical_specialty Very low-density lipoprotein Standardization Apolipoprotein B biology Cholesterol business.industry Biochemistry (medical) Clinical Biochemistry Bioinformatics Cholesterol triglycerides chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine biology.protein LDL Cholesterol Lipoproteins lipids (amino acids peptides and proteins) business Lipoprotein |
| Zdroj: | Laboratory Medicine. 39:481-490 |
| ISSN: | 0007-5027 |
| Popis: | This review evaluates the status of standardization of lipids and lipoproteins. Prerequisites and some basic principles for standardization are provided. The reference systems for cholesterol, HDL cholesterol (HDL-C), LDL cholesterol (LDL-C), triglycerides (TG), apolipoprotein A-I (apoA-I), apolipoprotein B (apoB), and lipoprotein(a) (Lp[a]) are described. Brief descriptions of the standardization programs available for each of these analytes are also provided. Finally, the review addresses some of the challenges in standardizing these markers of cardiovascular disease (CVD). The standardization programs described have contributed to improvements in laboratory measurements of lipids and lipoproteins. Our intention is that clinical laboratory professionals and manufacturers of in vitro diagnostics will use these resources to standardize lipid and lipoprotein measurements. Manufacturers must take the initiative to thoroughly evaluate their products and ensure traceability to the reference systems. |
| Databáze: | OpenAIRE |
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