Asymmetric Reactions Catalyzed by Chiral Metal Complexes. L. Synthesis of atropisomeric biphenylbisphosphine, 6,6'-bis(dicyclohexylphosphino)-3,3'-dimethoxy-2,2',4,4'-tetramethyl-1,1'-biphenyl and its use in rhodium(I)-catalyzed asymmetric hydrogenation

Autor:	Kazuo Achiwa, Toshiaki Morimoto, Masanao Murata, Naoko Yamamoto, Kiyoshi Yoshikawa
Rok vydání:	1991
Předmět:	Biphenyl Asymmetric hydrogenation Absolute configuration chemistry.chemical_element General Chemistry General Medicine Medicinal chemistry Catalysis Rhodium chemistry.chemical_compound chemistry Drug Discovery Itaconic acid Derivative (chemistry) BINAP
Zdroj:	Chemical and Pharmaceutical Bulletin. 39:2767-2769
ISSN:	1347-5223 0009-2363
Popis:	An optically pure atropisomeric biphenylbisphosphine, Cy-BIMOP, has been prepared, and its rhodium(I) complex showed higher catalytic activity and better enantioselectivity with the reverse configuration than BIMOP, p-MeO-BIMOP, and BINAP in the asymmetric hydrogentions of (Z)-α-acetamidoxinnamic acid, itaconic acid, and its derivative.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dd21271b2b7c4dce1333638b0bfe8df6 https://doi.org/10.1248/cpb.39.2767 Zobrazit plný text záznamu