Undergraduate Analytical Chemistry: Method Development and Results of the Analysis of Bismuth in Pharmaceuticals

Autor:	Rebekah Kimbrough, Brent Ferguson, Marina C. Koether
Rok vydání:	2010
Předmět:	Analytical chemistry chemistry.chemical_element Atomic and Molecular Physics and Optics Complexometric titration Analytical Chemistry law.invention Bismuth Ultraviolet visible spectroscopy chemistry law Reagent Standard addition Calibration Atomic absorption spectroscopy Spectroscopy
Zdroj:	Spectroscopy Letters. 43:545-549
ISSN:	1532-2289 0038-7010
DOI:	10.1080/00387010.2010.510764
Popis:	Three different methods were developed and employed to analyze the concentration of bismuth subsalicylate in an oral liquid pharmaceutical suspension. These methods were UV-Visible spectroscopy utilizing the external calibration method and the standard addition method, flame atomic absorption spectroscopy, and complexometric titration with EDTA. All three methods were conducted within one 3-hr period by undergraduate students in analytical chemistry laboratory class settings and produced results within the allowable range of 90.0–110.0% as listed in the United States Pharmacopeia. Differences in sensitivity, precision, sample size, time, and reagent use between the three methods were observed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dcf0009c8033a9d213eed127c238496e https://doi.org/10.1080/00387010.2010.510764 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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