The efficiency of IVF/ICSI protocols in female subclinical hypothyroidism and thyroid autoimmunity
| Autor: | Dariko A. Niauri, Lyailya Kh. Dzhemlikhanova, Galina Kh. Safaryan, Alexander M. Gzgzyan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Infertility
endocrine system Pediatrics medicine.medical_specialty 030219 obstetrics & reproductive medicine Assisted reproductive technology endocrine system diseases biology business.industry medicine.medical_treatment Levothyroxine Obstetrics and Gynecology 030209 endocrinology & metabolism medicine.disease Embryo transfer Miscarriage 03 medical and health sciences 0302 clinical medicine Thyroid peroxidase medicine biology.protein business Ovarian reserve Embryo quality medicine.drug |
| Zdroj: | Journal of obstetrics and women's diseases. 68:83-94 |
| ISSN: | 1683-9366 1684-0461 |
| DOI: | 10.17816/jowd68483-94 |
| Popis: | While overt hypothyroidism is a well-known risk factor for infertility, the association of subclinical hypothyroidism (SCH) or thyroid autoimmunity with reproductive failure has been still not cleared. This literature review focuses on the most current data linking SCH and/or thyroid autoimmunity with human reproduction, starting with the parameters of ovarian reserve and ending with generalized immunological alterations. The main ART outcome measures are as follows: number of oocytes retrieved, fertilization rate, embryo quality, implantation rate, clinical pregnancy rate per embryo transfer, miscarriage rate, and live birth rate. Summary of the information regarding the effect of levothyroxine supplementation on IVF outcome as well as workup and management of women with SCH and thyroid autoimmunity undergoing ART cycles is also presented in this review. |
| Databáze: | OpenAIRE |
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