P4730Underweight is associated with unfavourable short- and long-term outcomes after MitraClip therapy: a body mass index derived subgroup analysis of the German Transcatheter Mitral Valve Interventions (
| Autor: | Horst Sievert, R. S. von Bardeleben, Daniel Kalbacher, Jennifer Franke, Edith Lubos, Peter Boekstegers, Holger Eggebrecht, Taoufik Ouarrak, Christine S. Zuern, Björn Plicht, Eike Tigges, Miriam Puls, Georg Nickenig, Julia C. Senges |
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| Rok vydání: | 2019 |
| Předmět: |
2. Zero hunger
medicine.medical_specialty business.industry MitraClip Psychological intervention Commutator subgroup 030204 cardiovascular system & hematology language.human_language 3. Good health German 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Internal medicine Mitral valve language medicine Long term outcomes Cardiology Cardiology and Cardiovascular Medicine business Body mass index |
| Zdroj: | European Heart Journal. 40 |
| ISSN: | 1522-9645 0195-668X |
| DOI: | 10.1093/eurheartj/ehz745.1106 |
| Popis: | Background Underweight and obesity represent classical risk factors for patients undergoing cardiac surgery or interventional treatment. The multicentre German Transcatheter Mitral Valve Interventions (TRAMI) registry comprises a large and prospectively enrolled real-world cohort of patients treated by MitraClip implantation. Aims The current analysis examines the impact of underweight, overweight and obesity on intra-hospital, short and long-term outcomes in patients treated by MitraClip therapy. Methods and results From 08/2010 until 07/2013, 799 patients (age 75.3±8.6 years, male gender 60.7%, median logistic EuroSCORE 20% [12; 31], functional mitral regurgitation (MR): 69.3%) were prospectively enrolled into the multicentre, industry-independent German Transcatheter Mitral Valve Interventions registry. Patients were stratified according to body mass index (BMI) into four groups: BMI Conclusion Underweight patients are exposed to increased rates of procedural failure, bleeding and low cardiac output as well as increased short- and long-term mortality rates when undergoing MitraClip implantation and should therefore be carefully discussed within the heart team. Acknowledgement/Funding The TRAMI registry has been supported by proprietary means of IHF. Additional funding is provided by “Deutsche Herzstiftung” and a grant from Abbott. |
| Databáze: | OpenAIRE |
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