Obesity in Liver Transplantation: A Risk Factor for Unplanned Reoperation and Prolonged Operative Time

Autor:	Sunil K. Geevarghese, Saad C. Rehman, Kristina Gloria Jacomino, Eric S. Wise, James S. Ford, Michelle Izmaylov, Michael J. Maggart
Rok vydání:	2019
Předmět:	Univariate analysis medicine.medical_specialty Multivariate analysis business.industry medicine.medical_treatment Retrospective cohort study General Medicine Odds ratio Liver transplantation Logistic regression medicine.disease Obesity Internal medicine medicine Risk factor business
Zdroj:	The American Surgeon. 85:927-933
ISSN:	1555-9823 0003-1348
Popis:	Selection of orthotopic liver transplantation (OLT) candidates is increasingly inclusive of patients with high BMI. We aim to characterize the influence of obesity on the surgical outcome measures of prolonged operative time and unplanned reoperation. We reviewed the records of obese and normal weight OLT recipients over a 10-year period from a single institution. Variables that trended ( P < 0.1) with endpoints on univariate analysis were put into multivariate logistic regression models to determine independent association ( P < 0.05). We included 195 obese and 171 normal weight OLT recipients in our study. On multivariate analysis, obesity was the only preoperative risk factor that trended with unplanned reoperation (odds ratio 2, P = 0.05). Similarly, only obesity remained independently associated with prolonged length of operation (defined as ≥275 minutes) on multivariate analysis (odds ratio 1.7, P = 0.04). In summary, obesity may make OLT more technically challenging and, thus, represents an independent risk factor for unplanned reoperations and prolonged operative time.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dcd787375e0900f630bfb52774893651 https://doi.org/10.1177/000313481908500850 Zobrazit plný text záznamu