| Popis: |
The palatine tonsils and the appendix are components of mucosa-associated lymphoid tissue (MALT), namely the peripheral part of the immune system, which provides a protective barrier of mucous membranes against foreign antigens. Topographic and anatomical unity of the lymphoid apparatus of the pharynx and abdominal organs determine their direct lymphatic connection. Despite the progress achieved in the study of the etiology and pathogenesis of chronic tonsillitis and the pathology of the appendix, surgical treatment of these diseases remains the main one. The question of the influence of tonsillectomy and appendectomy on the state of humoral immunity remains controversial. The mechanisms of interaction of various links of humoral immunity in the formation of conjugated diseases of the lymphoid apparatus of the pharynx and abdominal cavity, namely, the palatine tonsils and the appendix, as well as statistical, clinical, immunological and morphological indicators concerning 940 patients with acute appendicitis at the age from 3 to 18 years old, who were undergoing treatment at the Kruglaya Multidisciplinary Center for the period from 2015 to 2018. The analysis of the statistical, seasonal, age and gender characteristics of the prevalence of acute appendicitis (AA), suggesting a connection with infectious and inflammatory diseases of the pharynx. Clinical cases showing the combination of tonsillar pathology and AA are presented. Based on the data obtained, similar immune-morphological changes in the palatine tonsils and the appendix were revealed during their inflammation, and the possible immune mechanisms of the pathogenesis of AA in tonsillar pathology were substantiated. Keywords: acute and chronic tonsillitis, complications, appendicitis. |
