Inhibition of Human Mixed Lymphocyte Reactions by Monoclonal Antibodies to Intercellular Adhesion Molecule-1 (ICAM-1)

Autor: Robert Rothlein, Chester Wood, Ronald B. Faanes, Carol D. Stearns, Kathleen Last-Barney, Vincent J. Merluzzi
Rok vydání: 1990
Předmět:
Zdroj: Leukocyte Adhesion Molecules ISBN: 9781461279273
DOI: 10.1007/978-1-4612-3234-6_20
Popis: Cell-cell adhesion is believed to be an integral event in the development of effective immunological responses. A family of molecules has been described which mediate leukocyte cell-cell and cell-substrate adhesions and are necessary for cell migration through endothelium. This family has been designated the lymphocyte function-associated antigen-1 (LFA-1)1 family or the CD18 complex of adhesion molecules (1–10).
Databáze: OpenAIRE