A New Diagnostic Approach to Assessing Tissue Changes in Type 2 Diabetes Mellitus in Mice Using 'LASMA ST' Device

Autor:	O. I. Stepanova, R. A. Klesov, Kh. Kh. Semenov, I. A. Pomytkin, V. N. Karkischenko
Rok vydání:	2022
Předmět:	General Medicine
Zdroj:	Journal Biomed. 18:37-44
ISSN:	2713-0428 2074-5982
DOI:	10.33647/2074-5982-18-3-37-44
Popis:	For the first time, LASMA ST, a device for laser diagnostic, was adapted for preclinical studies on laboratory db/db mouse genetic models of type 2 diabetes. The proposed method for studying of tissue changes during diabetes mellitus consists in a simultaneous control of microcirculation compartments: blood and lymph flow and oxidative coenzymes. The presented approach is characterized by a high informational value, safety and objectivity, as well as by the possibility of dynamic monitoring and obtaining online data on tissue metabolism (reduced nicotinamide adenine dinucleotide - NADH and oxidized flavin adenine dinucleotide - FAD).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dcb12e92e839d729fabf08a3baa10d07 https://doi.org/10.33647/2074-5982-18-3-37-44 Zobrazit plný text záznamu