Gender differences in the lumen of the left anterior descending artery—An autopsy based histomorphometric study

Autor: Sapna Patel, H.V. Chandrakanth, Pravinkumar N. Kamaradgi, Tanuj Kanchan, Alok Atreya, M. Arun
Rok vydání: 2016
Předmět:
Zdroj: Journal of the Anatomical Society of India. 65:65-68
ISSN: 0003-2778
DOI: 10.1016/j.jasi.2017.01.005
Popis: Introduction The prevalence of coronary artery disease is comparatively higher in males than females. The present research studies the sexual dimorphism in the luminal diameter of the left anterior descending artery. Methods The study was conducted on 35 male and 35 female cadaver hearts. This histomorphometric study was performed by using the computer assisted microscope, to understand the gender based variation in the arterial lumen. Results The study observed that the luminal diameter of the left anterior descending artery was higher in males. However, on correction with the weight of the heart, females showed a significantly wider coronary artery lumen, possibly indicating a better coronary flow in female hearts. Discussion The study observation suggests how the females are better protected from the coronary artery disease than the males. More elaborate studies on larger sample are suggested to confirm the observations of the present study.
Databáze: OpenAIRE