Echocardiographic estimation of left ventricular and pulmonary pressures in patients with heart failure and preserved ejection fraction: a study utilizing simultaneous echocardiography and invasive measurements
| Autor: | Michiel Rienstra, Peter van der Meer, Yoran M. Hummel, Elke S. Hoendermis, Adriaan A. Voors, Daniel F. Fonseca-Munoz, Licette C. Y. Liu, Carolyn S.P. Lam, Kevin Damman, Stephan Rosenkranz, Dirk J. van Veldhuisen |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Ejection fraction business.industry Atrial fibrillation Stroke volume 030204 cardiovascular system & hematology medicine.disease Pulmonary hypertension 03 medical and health sciences Preload 0302 clinical medicine Internal medicine Heart failure medicine Cardiology 030212 general & internal medicine Cardiology and Cardiovascular Medicine Pulmonary wedge pressure Heart failure with preserved ejection fraction business |
| Zdroj: | European Journal of Heart Failure. 19:1651-1660 |
| ISSN: | 1388-9842 |
| DOI: | 10.1002/ejhf.957 |
| Popis: | Aims Although echocardiography is generally used for the diagnosis of heart failure with preserved ejection fraction (HFpEF), invasive measurements of filling pressures are the gold standard. Studies simultaneously performing echocardiography and invasive measurements in HFpEF are sparse. Methods and results Invasive haemodynamic and echocardiographic measurements were simultaneously performed in 98 patients with heart failure New York Heart Association class ≥II, left ventricular ejection fraction (LVEF) ≥45%, and suspected pulmonary hypertension on a previous echocardiogram. Multivariable linear regression analyses were used to establish echocardiographic predictors of pulmonary artery wedge pressure (PAWP), left ventricular end-diastolic pressure (LVEDP), and mean pulmonary arterial pressure (mPAP). Mean age of the study patients was 74 ± 9 years, 68% were female, mean LVEF was 57 ± 5%, and 30% had atrial fibrillation at the time of measurement. Mean PAWP, LVEDP and mPAP were 17.2 ± 6.2, 16.7 ± 5.8 and 30.9 ± 10.2 mmHg, respectively. Isovolumetric relaxation time (IVRT) and left atrial reservoir strain could moderately estimate PAWP (r = 0.656; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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