Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit

Autor: Kelly A. Reagan, David M. Chan, Ginger Vanhoozer, Gonzalo Bearman
Rok vydání: 2023
Předmět:
Zdroj: Infection Control & Hospital Epidemiology. :1-6
ISSN: 1559-6834
0899-823X
DOI: 10.1017/ice.2023.37
Popis: Objective: To model the effects of active detection and isolation (ADI) regarding Clostridioides difficile infection (CDI) in the bone marrow transplant (BMT) unit of our hospital. Setting: ADI was implemented in a 21-patient bone marrow unit. Patients: Patients were bone marrow recipients on this unit. Interventions: We compared active ADI, in which patients who tested positive for colonization of C. difficile before their hospital stay were placed under extra contact precautions, with cases not under ADI. Results: Within the BMT unit, ADI reduced total cases of CDI by 24.5% per year and reduced hospital-acquired cases by ∼84%. The results from our simulations also suggest that ADI can save ∼$67,600 per year in healthcare costs. Conclusions: Institutions with active BMT units should consider implementing ADI.
Databáze: OpenAIRE