| Popis: |
Toxicology information systems have evolved swiftly from early, library-based bibliographic tools to advanced packages utilizing sophisticated computer and telecommunication technologies. These systems have evolved concurrently with the rapid expansion of the science of toxicology itself. Bibliographic files such as TOXLINE represent first attempts to handle the toxicology literature through online retrieval. Subsequent approaches applied the use of computers to provide literature-derived data, as in the HSDB or RTECS databanks, or to capture data directly from the laboratory. More advanced systems are utilizing computational and analytical approaches to extract knowledge from the laboratory data to predict outcomes. Societal concerns about hazardous substances, manifested in legislation and regulations, have been responsible for the generation of much toxicity information and the impetus to systematically collect and disseminate these data. Scientific progress in molecular biology, chemistry, and bioinformatics combined with advances in information technologies are also impacting the supply of toxicology information. The amount of information has risen dramatically over the years and it is more accessible and current than ever before. However, in order to derive meaning from the mounds of data and information, the field must rise to the challenge of fostering data accessibility, promoting data standards, and ensuring data quality. |
