Effect of Leu- and Met-enkephalins on brain reinforcing systems
Autor: | M. I. Titov, Andreev Bv, Yu. D. Ignatov, V. S. Kovalenko |
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Rok vydání: | 1981 |
Předmět: | |
Zdroj: | Bulletin of Experimental Biology and Medicine. 92:893-895 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/bf00836990 |
Popis: | The reinforcing systems of the brain are known to play an important role in the formation of predilection for and dependence on drugs [3]. It has been suggested that the activity of these systems may be modulated by endogenous morphine-like peptides -enkephalins and endorphins [4]. However, information on the direct effect of enkephalins on the reinforcing system is limited and contradictory [i0, 12]. Moreover, there have been virtually no studies of the effect of Leuand Met-enkephalins (LE and ME respectively) on the "punishment" system. |
Databáze: | OpenAIRE |
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