Autor: E. Yu. Sherstoboev, O. S. Borsuk, A. A. Churin, N. V. Masnaya
Rok vydání: 2003
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 135:365-369
ISSN: 0007-4888
DOI: 10.1023/a:1024664815450
Popis: T cells were most sensitive to cyclophosphamide in DBA/2 mice, while in C57Bl/6 mice both T and B cells were sensitive. The formation of antibody-producing cells and the production of specific antibodies were delayed in DBA/2 mice immunized after pretreatment with antitumor drug. Accumulation of antibody-producing cells in the spleen was more active in immunized C57Bl/6 mice treated with cyclophosphamide compared to animals not treated with cyclophosphamide.
Databáze: OpenAIRE