(40) The stereochemistry of the inhibition of acetylcholinesterase with acetylcholine-mimetic 7-aza-2,4-dioxaphosphadecalins

Autor:	Stefan Furegati, Peter Rüedi, Oliver Zerbe
Rok vydání:	2005
Předmět:	chemistry.chemical_compound Chemistry Stereochemistry medicine Stereoisomerism General Medicine Nuclear magnetic resonance spectroscopy Toxicology Acetylcholinesterase Acetylcholine medicine.drug
Zdroj:	Chemico-Biological Interactions. :418-420
ISSN:	0009-2797
DOI:	10.1016/j.cbi.2005.10.085
Popis:	The irreversible inhibition of acetylcholinesterase with the decalin-type cis- and trans-3-fluoro-2,4-dioxa-7-aza-3-phosphadecalins was investigated by 31P-NMR spectroscopy. The stereochemical outcome (inversion or retention at the P-atom) is dependent on the structure of the inhibitors.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dc2020e8b774c6249d5ab873c5d282de https://doi.org/10.1016/j.cbi.2005.10.085 Zobrazit plný text záznamu Full Text from ScienceDirect