Effect of time and dietary supplementation with processed yeasts (Kluyveromyces fragilis) on immunological parameters in weaned piglets
| Autor: | Annette Simon, Jürgen Zentek, Birgit Keimer, Robert Pieper |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
0402 animal and dairy science 04 agricultural and veterinary sciences Kluyveromyces fragilis Biology 040201 dairy & animal science Yeast 03 medical and health sciences 030104 developmental biology Animal science Weaned piglets Gene expression Weaning Animal Science and Zoology Dietary supplementation Early phase Feces |
| Zdroj: | Animal Feed Science and Technology. 245:136-146 |
| ISSN: | 0377-8401 |
| DOI: | 10.1016/j.anifeedsci.2018.09.008 |
| Popis: | A feeding trial was conducted to investigate the effects of differently processed yeast products (hydrolyzed or non-hydrolyzed) derived from Kluyveromyces fragilis on immunological parameters of piglets in an early phase post weaning (d 1–14). A total of 48 male and female piglets (6.17 ± 0.32 kg BW, weaned at d 25) were allocated to three dietary groups (n = 8 replicates with two piglets each) receiving a control diet (CON) or diets with 1% non-hydrolyzed yeast (Diet NHY) or 1% hydrolyzed yeast (Diet HY). The piglets were fed isoenergetic and isonitrogenous diets and had ad-libitum access to feed (mash form) and drinking water. Blood samples were taken at d 1 and d 14 for differential blood count and phenotyping of lymphocytes and at d 1, d 3 and d 14 for analysis of phagocytic activity of leukocytes. Eight animals per treatment were sacrificed 2 weeks after weaning for jejunal and colonal tissue sampling for mRNA extraction and gene expression analysis of cytokines (TNFα, IL-6, IL-10, IL-12) and of tight junction proteins. Different treatments had no effect on piglet growth rate. Fecal scores were improved at d 8 after weaning in the yeast supplemented Groups HY and NHY (P |
| Databáze: | OpenAIRE |
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