Renal hemodynamic and diuretic effects of low-dosage dopamine in anesthetized cats

Autor:	Dean D. Schwartz, James S. Wohl, Clark Terrence Patrick, W. Shannon Flournoy, James C. Wright
Rok vydání:	2007
Předmět:	Mean arterial pressure CATS General Veterinary business.industry medicine.medical_treatment Dopaminergic Diuresis Renal function Blood pressure Anesthesia Renal blood flow Medicine Diuretic business
Zdroj:	Journal of Veterinary Emergency and Critical Care. 17:45-52
ISSN:	1476-4431 1479-3261
Popis:	Objective: To evaluate the effects of low-dosage (3 μg/kg/min) dopamine on urine output, renal blood flow, creatinine clearance, sodium excretion, heart rate, and mean arterial pressure (MAP) in healthy anesthetized cats. Design: Controlled experimental study. Setting: University experimental laboratory. Animals: Twelve random-bred 2–4-year-old cats. Interventions: Anesthesia, laparotomy for renal artery blood flow measurement, and arterial and venous catheterization. Measurements: Heart rate (HR), MAP, renal blood flow, urine output, sodium excretion, fractional sodium excretion, and creatinine clearance. Main results: No significant difference in urine output, sodium excretion, HR, or creatinine clearance occurred in cats receiving low-dosage dopamine. A transient decrease in the mean arterial blood pressure occurred in cats receiving dopamine. Conclusions: Low-dosage dopamine cannot be expected to induce diuresis in healthy cats. Low-dosage dopamine may cause vasodilation in non-renal vascular beds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dc0be831391eb2fe579cd5a527d17744 https://doi.org/10.1111/j.1476-4431.2006.00209.x Zobrazit plný text záznamu Plný text