Structure and Biological Activity of Galactomannans from Seed Pods of Two Crotalaria Species

Autor:	O. B. Shadybekova, F. A. Kodiralieva, L. I. Shevchenko, R. K. Rakhmanberdyeva
Rok vydání:	2020
Předmět:	chemistry.chemical_classification biology 010405 organic chemistry Crotalaria Biological activity Plant Science General Chemistry bacterial infections and mycoses biology.organism_classification Polysaccharide 01 natural sciences Anticoagulant activity General Biochemistry Genetics and Molecular Biology 0104 chemical sciences carbohydrates (lipids) 010404 medicinal & biomolecular chemistry Galactomannan chemistry.chemical_compound Sulfation chemistry Crotalaria alata Food science skin and connective tissue diseases
Zdroj:	Chemistry of Natural Compounds. 56:985-989
ISSN:	1573-8388 0009-3130
DOI:	10.1007/s10600-020-03210-z
Popis:	Water-soluble polysaccharides and pectinic substances from seed pods of Crotalaria alata L. (Uzbekistan) and Crotalaria sp. (India) were studied. The water-soluble polysaccharides were found to dominate over pectinic substances. Galactomannan GM-SP with a Man:Gal ratio of 4.4:1 was isolated from Crotalaria sp. seed pods. Its main chain consisted of 1,4-β-bound polymannans with 1,6-α-bound galactopyranose side residues. Sulfated derivatives of galactomannan from C. alata were prepared. The supramolecular structures of the galactomannan and its sulfated derivative were studied using electron microscopy. The galactomannan sulfated derivative exhibited anticoagulant activity.
Databáze:	OpenAIRE
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